Many organic compounds contain two or more functional groups in the same molecule. This carboxyl group may be the same as the one associated with proton-anion cotransport. Here the functional group and class name are the same. This indicates that a reactive carboxyl group constitutes part of the permeability barrier to net conductive anion transport through band 3. A carboxyl group consists of a carbon double-bonded to oxygen and singly bonded to a hydroxyl group. It can be referred to as a carboxy group, a carboxyl functional group, or a carboxyl radical.

This group is made up of two other functional groups. A carboxyl is a common functional group in organic chemistry. Finally, conversion of band 3 carboxyl groups to alcohols (again under conditions of minimal permeation of the reagent) causes a nearly 10-fold increase in stilbene disulfonate-sensitive Cl conductance. The definition above tells us that carboxylic acids all contain the carboxyl functional group, -COOH. The general formula of a carboxylic acid is R-COOH. This result provides evidence against the idea that either of the reactive carboxyl groups participates in a 'zipper' transport mechanism, in which anions and protein-bound negative charge move in opposite directions. In chemistry, carboxylic acids are generally weak organic acids that contain a carboxyl functional group. A set of experiments was performed to determine the effect of the Cl gradient on the labeling of both the 60-kD and 35-kD chymotryptic fragments. These results all indicate that the carboxyl group associated with proton-SO4 cotransport is not removed by papain and is in the COOH-terminal 28-kD fragment. In organic chemistry, a carboxylate is the conjugate base of a carboxylic acid, RCOO (or RCO2). Papain itself does not inhibit the proton-SO4 cotransport that takes place during Cl/SO4 exchange. In this structure of a carboxyl group, a carbon atom is attached to an oxygen atom with the help of a double. There is significant labeling in the 28-kD papain fragment, but not in the 7-kD papain fragment. Chemical modification and proteolytic digestion have been used to examine three aspects of the role of carboxyl groups in the anion transport catalyzed by. functional group name polar/nonpolar reactivity/notable trait. Carboxyl group is a functional organic compound. Carboxyl groups in both major chymotryptic fragments are labeled, with most of the label in the 35-kD COOH-terminal fragment. The reagent, with radioactive BH4, can be used to label reactive carboxyl groups in intact cells under conditions in which only extracellular residues are labeled. The modification employs the negatively charged Woodward's reagent K and BH4, which together can convert protein carboxyl groups to alcohols (Jennings and Anderson, 1987). Chemical modification and proteolytic digestion have been used to examine three aspects of the role of carboxyl groups in the anion transport catalyzed by the red cell inorganic anion-exchange protein (known as band 3 or capnophorin).

Carboxyl functional group